九州大学 先導物質化学研究所 講演会
日 時 ： 2014年1月9日（木） 15:00-16:30
場 所 ： 箱崎地区先導研会議室（旧工学部３号館114会議室）
題 目 ： 「Photo-assisted surface control of polymer films for cell engineering」
講 師 ： Prof. Eunkyoung Kim
（Department of Chemical and Biomolecular Engineering, Yonsei University Active Polymer Center for Pattern Integration (APCPI)）
Surface properties of conjugated polymer films could be tuned by photoreaction of unsaturated bonds of the polymer. Such patterning approaches have greatly profited as a direct photopatterning method rendering cell adhesive surface. Patterns of human bone marrow-derived mesenchymal stem cells (MSCs) were produced through the photo-assisted surface engineering of polymer coated cell culture substrates, which has promoted new insights into the factors that control cell adhesion to polymer surfaces, cell proliferation, differentiation. On the other hands, by controlling the NIR absorption of a conjugated polymer film, the proliferation and harvesting of MSCs on the surface were controlled quantitatively. This light-induced cell detachment method based on polymer films provides the temporal and spatial control of cell harvesting, as well as cell patterning. The harvested MSCs by this method preserved their intrinsic characteristics as well as multilineage differentiation capacities.
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